TY - JOUR PY - 2016// TI - A rare outcome induced by metformin intoxication: Severe lactic acidosis and hepatotoxicity JO - BANTAO Journal A1 - Elyigit, F. A1 - Akar, H. A1 - Soyaltin, U.E. A1 - Ekinci, F. SP - 45 EP - 47 VL - 14 IS - 1 N2 - Metformin is a widely used oral anti-diabetic agent that decreases insulin resistance. Lactic acidosis rarely develops with this medication. Metformin-induced hepatotoxicity has been rarely reported in the literature. We describe a patient, who presented with lactic acidosis and hepatotoxicity after ingestion of 40 pills of metformin in order to commit suicide. The most important treatment step in patients with metformin-associated lactic acidosis (MALA) is high-volume hemodialysis and hemofiltration.

Language: en

LA - en SN - 1312-2517 UR - http://dx.doi.org/10.1515/bj-2016-0011 ID - ref1 ER -