TY - JOUR PY - 2013// TI - Pathological findings of myocardium in carbon monoxide poisoning are basically similar to those in hypothermic deaths JO - Anil Aggrawal's internet journal of forensic medicine and toxicology A1 - Morita, S. A1 - Furukawa, S. A1 - Wingenfeld, L. A1 - Nishi, K. SP - EP - VL - 14 IS - 2 N2 - It has been described that the myocardium did not show any ischemic types of changes or other lesions in human hearts obtained from fatal carbon monoxide poisoning cases, although some report indicated the existence of pathological changes in the myocardium from carbon monoxide poisoning cases. We investigated the changes in myocardium obtained from several individuals who died in suicidal carbon monoxide poisoning, in house fire cases and in suicidal burning with kerosene using conventional staining. And we compared the results with those obtained from individual who died due to hypothermia. With conventional staining the cardiac cells from both group showed color-changing with HE (eosinphilic color changing) and Azan (orange color changing) stains, colliquative myocytolysis and contraction bands necrosis, respectively, however aggregated cardiac cells was find only in those from hypothermic death. The results obtained in this study and together with previous one indicate that death mechanism of carbon monoxide poisoning and hypothermic resemble to each other, that is, cardiac hypoxia is surely caused by disturbance of oxygen releasing from hemoglobin in hypothermia and by lacking of oxygen due to high affinity of carbon-monoxide to hemoglobin in CO poisoning, respectively.
Language: en
LA - en SN - 0972-8066 UR - http://dx.doi.org/ ID - ref1 ER -