TY - JOUR PY - 2011// TI - Early intervention in psychosis: Clinical aspects of treatment JO - Advances in psychiatric treatment A1 - Murphy, B.P. A1 - Brewer, W.J. SP - 408 EP - 416 VL - 17 IS - 6 N2 - Engaging patients in first-episode psychosis services is critical in maximising the effect of early intervention and establishing a framework for longer-term treatment. Biopsychosocial assessments determine a working diagnosis and inform evidence-based treatment. Atypical antipsychotics should be used at doses that maximise therapeutic benefit and adherence while minimising side-effects. Patients are helped to construct a narrative of their illness, including a shared understanding of the contribution of biological and environmental risks, and early warning signs. Common comorbid conditions, including depression, suicidal ideation, substance misuse and anxiety, should be addressed. Management of comorbid borderline and antisocial personality disorders is difficult; their nexus with psychosis is discussed. Cognitive-behavioural therapy is a mainstay of treatment, with specific interventions developed for problems typical in first-episode presentations. Core psychosocial interventions include psychoeducation, vocational and educational support, family interventions and multimodal group programmes.
Language: en
LA - en SN - 1355-5146 UR - http://dx.doi.org/10.1192/apt.bp.111.008979 ID - ref1 ER -