TY - JOUR PY - 2004// TI - Pegylated interferons JO - Journal of Drug Evaluation A1 - D'Souza, R. A1 - Foster, G.R. SP - 113 EP - 127 VL - 2 IS - 4 N2 - PEG-interferons have improved pharmacokinetics by allowing a once-weekly dosing regimen that provides constant and sustained therapeutic plasma concentrations, and, as a result, a constant and sustained antiviral pressure over the entire dosing period. This in turn, leads to PEG-IFN having significantly improved response rates over conventional IFN in patients suffering from chronic hepatitis B and C, and it is likely that the improved response rates with these new compounds will lead to more patients eradicating these life threatening viruses. © 2004 Parthonon Publishing.

Language: en

LA - en SN - 1479-1137 UR - http://dx.doi.org/10.1080/14791130400023643 ID - ref1 ER -