TY  - JOUR
PY  - 2004//
TI  - Clinical analysis of neuropsychiatric involement in severe acute respiratory syndrome
JO  - Chinese Journal of Neurology
A1  - Tang, Y.-m.
A1  - Xing, Y.-g.
A1  - Li, J.-g.
A1  - Ding, Y.-q.
A1  - Lei, C.-l.
A1  - Tang, X.-p.
SP  - 228
EP  - 230
VL  - 37
IS  - 3
N2  - OBJECTIVE: To investigate the clinical features of severe acute respiratory syndrome (SARS) with neuropsychiatric involement. <br><br>METHODS: The clinical data of 173 patients of SARS with neuropsychiatric involement were retrospectively reviewed. <br><br>RESULTS: (1) The incidence of neuropsychiatric involement of SARS is about 53.2%. The manifestations mostly consist of: headache 67.1% ,dizziness 28.9%, consciousness disorder 10.4%, mental disorder 4.6%, focal manifestations 0.6%, seizures 1.2%, affective disorder 30.6%, in which anxiety 20.2%, depression 6.4%, tendency of committing suicide 1.2%, phobia 7.5%. (2) The number of serious cases with neuropsychiatric involement were much more than those of slight cases, P <0.01. (3) Ophthalmoscopic examination was performed for four patients and showed that the outline of optic disc was blurred, and the retinal veins were congestive. (4) Pathological characteristics of 2 cases: edema of the perivascular tissue and vascular wall of the small veins accompanying with mononuclear cells and lymphocytes infiltration, neuron degeneration and demyelination distributing in the brain. <br><br>CONCLUSIONS: The manifestation of neuropsychiatric involement is variable, and is associated with the severity of SARS. The typical pathological change is edema, localized necrosis and neuron degeneration and demyelination.<p /> <p>Language: zh</p>
LA  - zh
SN  - 1006-7876
UR  - http://dx.doi.org/
ID  - ref1
ER  -