TY - JOUR PY - 2002// TI - Depression JO - Revista brasileira de medicina A1 - Del Porto, J.A. SP - 97 EP - 107 VL - 59 IS - SPEC. ISS. N2 - The author begin giving epidemiologic data, as the more frequent complaints, poiting out the anamnesis' importance, not only to detect the "secondary" depressions (with origin in organic diseases) as to detect more specific depression symptoms. Then presents the clinical features of depression taking into consideration: 1) psychic; 2) physiologic symptoms; and 3) behavioural evidences that establish the diagnosis, such as the depressive humor, satisfaction feeling reduction, fatigue, thinking reduced capacity, sleep, eating and behavioural disturbances (social detriment, cry, suicide tendencies, psychomotor retardation), pointing out the frequent anxiety association. The author also show the circadian rythm modification and sequentially presents the bipolar disorders spectrum and depression: (bipolar I, bipolar II, associated with hypomania, recurrent depression - without hypomania, with familiar history) the so-called bipolat III (pseudo unipolar); he follows with the DSM-IV guidelines, discussing the several diseases spectrum. Besides the classification data, he defines the depression limits and the personality disorders limits, presenting also the differential diagnostic with other psychiatric disorders. Regarding to treatment of the depressive disorders, the author presents the therapeutic plan (association with the patient, disease education approach with the family, pharmacologic or eletroconvulsant facilities and the psychoterapy). About the antidepressive (AD) agents, the author describes the triciclic and tetraciclics AD, the selective reuptake serotonine inhibitors (SRSI), that are more recent, concluding with other AD of newer therapeutic introduction. For all the presented drugs, the side-effects, drug interactions and tolerability, are presented.

Language: pt

LA - pt SN - 0034-7264 UR - http://dx.doi.org/ ID - ref1 ER -