TY  - JOUR
PY  - 2024//
TI  - Three cases of chemical burns caused due to dimethyl sulfate poisoning
JO  - Curēus
A1  - Mizuta, Shiori
A1  - Miyakoshi, Tatsuya
A1  - Matsui, Kotaro
A1  - Nakayama, Yuko
A1  - Koshida, Yosinao
SP  - e57060
EP  - e57060
VL  - 16
IS  - 3
N2  - Dimethyl sulfate (DMS) is a drug widely used as a pharmaceutical and synthetic raw material. On the other hand, it is highly toxic and requires management and treatment as a hazardous substance. A mass outbreak of chemical burns resulting from DMS poisoning occurred at a drug factory. All three patients were brought to our hospital, a tertiary emergency medical facility, several hours after exposure. Their vital signs were stable, with only eye pain and a sore throat. However, after admission, two patients required emergency tracheostomy or endotracheal intubation due to laryngeal edema. Improvement was achieved through the administration of steroids, but a severely injured patient required an extended treatment period. DMS poisoning is rare; however, it can be fatal depending on the exposure concentration. Furthermore, even if the initial symptoms are mild, laryngeal edema may develop later, requiring careful monitoring and appropriate airway interventions.<p />  <p>Language: en</p>
LA  - en
SN  - 2168-8184
UR  - http://dx.doi.org/10.7759/cureus.57060
ID  - ref1
ER  -