TY - JOUR
PY - 2024//
TI - An 18-year, single centre, retrospective study of long-term neurological outcomes in paediatric submersion-related cardiac arrests
JO - Resuscitation plus
A1 - Scharink, Denne
A1 - Hunfeld, Maayke
A1 - Albrecht, Marijn
A1 - Dulfer, Karolijn
A1 - de Hoog, Matthijs
A1 - van Gils, Annabel
A1 - de Jonge, Rogier
A1 - Buysse, Corinne
SP - e100632
EP - e100632
VL - 18
IS -
N2 - Aim Investigate long-term outcome in paediatric submersion-related cardiac arrests (CA). Methods Children (age one day-17 years) were included if admitted to the Erasmus MC Sophia Children's Hospital, after drowning with CA, between 2002 and 2019. Primary outcome was survival with favourable neurological outcome, defined as a Paediatric Cerebral Performance Category (PCPC) score of 1-3 at longest available follow-up. Secondary outcome were age-appropriate neuropsychological assessments at longest available follow-up. Results Upon hospital admission, 99 children were included (median age at time of CA 3.2 years [IQR 2.0-5.9] and 65% males). Forty children died in-hospital (no return of circulation (45%) or withdrawal of life sustaining therapies (55%)) and 4 children deceased after hospital discharge due to complications following the drowning-incident. Among survivors, with a median follow-up of 2.3 years [IQR 0.2-5.5], 47 children had favourable neurological outcome (i.e. PCPC 1-3) and 8 children unfavourable (unfavourable outcome group total n = 52, i.e. PCPC 4-5 or deceased). Twenty-six (47%) children participated in a neuropsychological assessment (median follow-up 4.0 years [IQR 2.3-8.7]). Compared with normative test data, participants obtained worse general (p = 0.008) and performance (p = 0.003) intelligence scores, processing speed (p = 0.002) and visual motor integration scores (p = 0.0012). Conclusions Although overall outcome in survivors was favourable at longest available follow-up, significant deficits in neuropsychological assessments were found. This study underlines the need for a standardized long term follow-up program as standard of care in paediatric drowning with CA. Language: en
LA - en
SN - 2666-5204
UR - http://dx.doi.org/10.1016/j.resplu.2024.100632
ID - ref1
ER -