TY  - JOUR
PY  - 2024//
TI  - Co-existence of depression and post-concussion syndrome one month after mild traumatic brain injury
JO  - Brain injury
A1  - Biard, Adam
A1  - Vaittinada Ayar, Prabakar
A1  - Diallo, Alhassane
A1  - Gatineau-Sailliant, Maryame
A1  - Lefevre, Clémence
A1  - Cogné, Mélanie
A1  - Azouvi, Philippe
A1  - Faillot, Thierry
A1  - Decq, Philippe
A1  - Faillot, Matthieu
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - BACKGROUND: Previous studies suggest an association between Post-concussion syndrome (PCS) and depression, both highly prevalent after mTBI. <br><br>OBJECTIVE: To assess the prevalence and risk-factors of depression among patients with PCS 1 month after mTBI. <br><br>METHODS: We prospectively screened 372 mTBI patients admitted in two academic Emergency Departments between 2017 and 2019. One month after mTBI, we administered the Rivermead Post-concussion symptoms Questionnaire (RPQ) and the Patient Health Questionnaire (PHQ-9) questionnaires over the telephone. PCS and depression were defined by RPQ ≥ 12 and PHQ-9 ≥ 10. Multivariate multinomial regression identified baseline factors associated with PCS and depression. <br><br>RESULTS: Two hundred and eight completed RPQ and PHQ-9. Forty-seven patients (22.5%) met criteria for PCS, among which 22 (46.8%) met criteria for depression (PCS+D+). Patients with PCS but without depression were less likely to present with an associated injury (Coefficient = -1.6, p = 0.047) and to report initial sadness (Coefficient = -2.5, p = 0.03). Initial sadness (Coefficient = -1.3, p = 0.047), associated injury (Coefficient = -1.9, p = 0.008), as well as initial nausea (Coefficient = -1.8, p = 0.002), and male sex (Coefficient = 1.8, p = 0.002), were associated with the absence of depression and PCS in comparison with PCS+D+ patients. <br><br>CONCLUSION: Among patients with PCS 1 month after mTBI, those with depression are more likely to present with initial sadness and with an associated injury.<p />  <p>Language: en</p>
LA  - en
SN  - 0269-9052
UR  - http://dx.doi.org/10.1080/02699052.2024.2311338
ID  - ref1
ER  -