TY  - JOUR
PY  - 2024//
TI  - Risky decision-making in major depressive disorder: a three-level meta-analysis
JO  - International journal of clinical and health psychology
A1  - Lu, Jiaqi
A1  - Zhao, Xu
A1  - Wei, Xuxuan
A1  - He, Guibing
SP  - e100417
EP  - e100417
VL  - 24
IS  - 1
N2  - BACKGROUND: Individuals with major depressive disorder (MDD) are usually observed making inappropriate risky decisions. However, whether and to what extent MDD is associated with impairments in risky decision-making remains unclear. We performed a three-level meta-analysis to explore the relationship between risky decision-making and MDD. <br><br>METHOD: We searched the Web of Science, PubMed, Scopus, and PsycINFO databases up to February 7, 2023, and calculated Hedges' g to demonstrate the difference in risky decision-making between MDD patients and healthy controls (HCs). The moderating effect of sample and task characteristics were also revealed. <br><br>RESULTS: Across 73 effect sizes in 39 cross-sectional studies, MDD patients exhibited greater risk-seeking than HCs (Hedges' g = 0.187, p = .030). Furthermore, age (p = .068), region (p = .005), and task type (p < .001) were found to have moderating effects. Specifically, patients preferred risk-seeking over HCs as age increased. European patients showed significantly increased risk-seeking compared to American and Asian patients. Patients in the Iowa Gambling Task (IGT) exhibited a notable rise in risk-seeking compared to other tasks, along with an increased risk aversion in the Balloon Analogue Risk Task (BART). The multiple-moderator analysis showed that only task type had significant effects, which may be explained by a tentative framework of "operationalization-mechanism-measure" specificity. <br><br>CONCLUSIONS: MDD patients generally exhibit higher risk-seeking than HCs. It implies that impaired risky decision-making might be a noteworthy symptom of depression, which should be placed more emphasis for clinical management and psycho-education.<p />  <p>Language: en</p>
LA  - en
SN  - 1697-2600
UR  - http://dx.doi.org/10.1016/j.ijchp.2023.100417
ID  - ref1
ER  -