TY  - JOUR
PY  - 2022//
TI  - Predicting vigilance vulnerability during 1 and 2 weeks of sleep restriction with baseline performance metrics
JO  - Sleep advances
A1  - Lo, June C.
A1  - Ang, Jit Wei A.
A1  - Koa, Tiffany B.
A1  - Ong, Ju Lynn
A1  - Lim, Julian
SP  - zpac040
EP  - zpac040
VL  - 3
IS  - 1
N2  - STUDY OBJECTIVES: We attempted to predict vigilance performance in adolescents during partial sleep deprivation using task summary metrics and drift diffusion modelling measures (DDM) derived from baseline vigilance performance. <br><br>METHODS: In the Need for Sleep studies, 57 adolescents (age = 15-19 years) underwent two baseline nights of 9-h time-in-bed (TIB), followed by two cycles of weekday sleep-restricted nights (5-h or 6.5-h TIB) and weekend recovery nights (9-h TIB). Vigilance was assessed daily with the Psychomotor Vigilance Task (PVT), with the number of lapses (response times ≥ 500 ms) as the primary outcome measure. The two DDM predictors were drift rate, which quantifies the speed of information accumulation and determines how quickly an individual derives a decision response, and non-decision time range, which indicates within-subject variation in physical, non-cognitive responding, e.g. motor actions. <br><br>RESULTS: In the first week of sleep curtailment, faster accumulation of lapses was significantly associated with more lapses at baseline (p =.02), but not the two baseline DDM metrics: drift and non-decision time range (p >.07). On the other hand, faster accumulation of lapses and greater increment in reaction time variability from the first to the second week of sleep restriction were associated with lower drift (p <.007) at baseline. <br><br>CONCLUSIONS: Among adolescents, baseline PVT lapses can predict inter-individual differences in vigilance vulnerability during 1 week of sleep restriction on weekdays, while drift more consistently predicts vulnerability during more weeks of sleep curtailment. CLINICAL TRIAL INFORMATION: Effects of Napping in Sleep-Restricted Adolescents, clinicaltrials.gov, NCT02838095. The Cognitive and Metabolic Effects of Sleep Restriction in Adolescents (NFS4), clinicaltrials.gov, NCT03333512.<p />  <p>Language: en</p>
LA  - en
SN  - 2632-5012
UR  - http://dx.doi.org/10.1093/sleepadvances/zpac040
ID  - ref1
ER  -