TY - JOUR PY - 2023// TI - Remote virtual reality assessment elucidates self-blame-related action tendencies in depression JO - Journal of psychiatric research A1 - Duan, Suqian A1 - Valmaggia, Lucia A1 - Fennema, Diede A1 - Moll, Jorge A1 - Zahn, Roland SP - 77 EP - 83 VL - 161 IS - N2 - BACKGROUND: Action tendencies are implicit cognitive and motivational states before an action is taken, such as feeling like hiding when experiencing shame or guilt, independent of the actions people decide to take. Such "action tendencies" are key to understanding the maladaptive impact of self-blame in depression. For example, feeling like "hiding" in a text-based task was previously associated with recurrence risk in remitted depression. Despite their functional importance, action tendencies have not been systematically investigated in current depression, which was the aim of this pre-registered study.

METHODS: We developed and validated the first virtual reality (VR) assessment of blame-related action tendencies and compared current depression (n = 98) with control participants (n = 40). The immersive VR-task, pre-programmed on devices sent to participants' homes, used hypothetical social interactions, in which either participants (self-agency) or their friend (other-agency) were described to have acted inappropriately.

RESULTS: Compared with controls, people with depression showed a maladaptive profile: particularly in the other-agency condition, rather than feeling like verbally attacking their friend, they were prone to feeling like hiding, and punishing themselves. Interestingly, feeling like punishing oneself was associated with a history of self-harm but not suicide attempts.

CONCLUSIONS: Current depression and self-harm history were linked with distinctive motivational signatures, paving the way for remote VR-based stratification and treatment.

Language: en

LA - en SN - 0022-3956 UR - http://dx.doi.org/10.1016/j.jpsychires.2023.02.031 ID - ref1 ER -