TY  - JOUR
PY  - 2023//
TI  - Do cortisol and dehydroepiandrosterone influence motivational factors for non-suicidal self-injury in female adolescents?
JO  - Journal of clinical medicine
A1  - Piarulli, Francesco Maria
A1  - Margari, Anna
A1  - Margari, Francesco
A1  - Matera, Emilia
A1  - Croce, Federica
A1  - Furente, Flora
A1  - Gabellone, Alessandra
A1  - Petruzzelli, Maria Giuseppina
SP  - e1924
EP  - e1924
VL  - 12
IS  - 5
N2  - Non-suicidal self-injury (NSSI) is a significant public health issue that particularly affects female adolescents usually emerging during puberty, with a subsequent reduction and even remission in the phenomenon later in life. The dysregulation of the hormonal stress response, particularly cortisol and dehydroepiandrosterone sulfate (DHEA-S), whose levels increase markedly during pubertal adrenarche, has been associated with the development and maintenance of a wide range of emotional disorders. Our study aims to investigate whether different cortisol-DHEA-S response patterns could be associated with the main motivational moderators to engage NSSI as well as with urgency and motivation to stop NSSI in a sample of female adolescents. We found significant correlations between stress hormones and several factors that support and sustain NSSI, specifically: cortisol levels and distressing/upsetting urge (r = 0.39 and a p = 8.94 × 10(-3)) and sensation seeking (r = -0.32 and a p = 0.04), as well as cortisol/DHEA-s ratio and external emotion regulation (r = 0.40 and a p = 0.01) and desire to stop NSSI (r = 0.40 and a p = 0.01). Cortisol and DHEA-S may play a role in NSSI through the regulation of stress responses and affective states. Such results could have implications for the development of new and improved treatment and prevention plans for NSSI.<p />  <p>Language: en</p>
LA  - en
SN  - 2077-0383
UR  - http://dx.doi.org/10.3390/jcm12051924
ID  - ref1
ER  -