TY  - JOUR
PY  - 2023//
TI  - Bidirectional comorbid associations between back pain and major depression in US adults
JO  - International journal of environmental research and public health
A1  - Yang, Haiou
A1  - Hurwitz, Eric L.
A1  - Li, Jian
A1  - de Luca, Katie
A1  - Tavares, Patricia
A1  - Green, Bart
A1  - Haldeman, Scott
SP  - e4217
EP  - e4217
VL  - 20
IS  - 5
N2  - Low back pain and depression have been globally recognized as key public health problems and they are considered co-morbid conditions. This study explores both cross-sectional and longitudinal comorbid associations between back pain and major depression in the adult population in the United States. We used data from the Midlife in the United States survey (MIDUS), linking MIDUS II and III with a sample size of 2358. Logistic regression and Poisson regression models were used. The cross-sectional analysis showed significant associations between back pain and major depression. The longitudinal analysis indicated that back pain at baseline was prospectively associated with major depression at follow-up (PR 1.96, CI: 1.41, 2.74), controlling for health behavioral and demographic variables. Major depression at baseline was also prospectively associated with back pain at follow-up (PR 1.48, CI: 1.04, 2.13), controlling for a set of related confounders. These findings of a bidirectional comorbid association fill a gap in the current understanding of these comorbid conditions and could have clinical implications for the management and prevention of both depression and low back pain.<p />  <p>Language: en</p>
LA  - en
SN  - 1661-7827
UR  - http://dx.doi.org/10.3390/ijerph20054217
ID  - ref1
ER  -