TY - JOUR PY - 2015// TI - Simulation of tissue damage of a perfused liver under dynamic compression loading using a liver finite element model JO - Transactions of Society of Automotive Engineers of Japan A1 - Sato, Fusako A1 - Yamamoto, Yoshihiro A1 - Takayama, Shinichi A1 - Ejima, Susumu A1 - Dokko, Yasuhiro A1 - Yasuki, Tsuyoshi SP - 139 EP - 144 VL - 46 IS - 1 N2 - A liver Finite Element (FE) model with hyper-viscoelastic properties was developed. Hyper-elastic and rate-dependent characteristics were modeled with Ogden rubber material model. Such characteristics were validated against an original series of porcine exsanguinated livers under quasi-static and dynamic compression experiments. The applicability of the validated liver FE model was evaluated against a series of compression tests with porcine perfused livers to model nearly in vivo conditions. The regions where the FE model showed highest strain concentrations corresponded with the regions where perfused livers tested under dynamic loading sustained tissue damage. Based on this correspondence, ultimate strains for hepatic parenchyma and membrane were estimated by comparing strain patterns of the FE model with damaged conditions of the tested livers.

Language: ja

LA - ja SN - 0287-8321 UR - http://dx.doi.org/10.11351/jsaeronbun.46.139 ID - ref1 ER -