TY - JOUR PY - 2022// TI - Neurocognitive outcomes of older National Football League retirees JO - Brain injury A1 - Schaffert, Jeff A1 - Didehbani, Nyaz A1 - LoBue, Christian A1 - Hart, John Jr A1 - Motes, Michael A1 - Rossetti, Heidi A1 - Wilmoth, Kristin A1 - Goette, Will A1 - Lacritz, Laura A1 - Cullum, C. Munro SP - ePub EP - ePub VL - ePub IS - ePub N2 - OBJECTIVE: Determine if head-injury exposure relates to later-in-life cognitive decline in older National Football League (NFL) retirees.

METHOD: NFL retirees (aged 50+) with or without cognitive impairment underwent baseline (n = 53) and follow-up (n = 29; 13-59 months later) neuropsychological evaluations. Cognitively normal (CN) retirees (n = 26) were age- and education-matched to healthy controls (n = 26). Cognitively impaired (CI) retirees with mild cognitive impairment or dementia (n = 27) were matched to a clinical sample (CS) by age, sex, education, and diagnosis (n = 83). ANOVAs compared neuropsychological composites at baseline and over time between retirees and their matched groups. Regression models evaluated whether concussions, concussions with loss of consciousness (LOC), or games played predicted neuropsychological functioning.

RESULTS: At baseline, CN retirees had slightly worse memory than controls (M(CN retirees) = 50.69, SE(CN retirees) = 1.320; M(Healthy controls) = 57.08, SE(Healthy controls) = 1.345; p = 0.005). No other group diferences were observed, and head-injury exposure did not predict neurocognitive performance at baseline or over time.

CONCLUSIONS: Head-injury exposure was not associated with later-in-life cognition, regardless of cognitive diagnosis. Some retirees may exhibit lower memory scores compared to age-matched peers, though this is of unclear clinical significance.

Language: en

LA - en SN - 0269-9052 UR - http://dx.doi.org/10.1080/02699052.2022.2143567 ID - ref1 ER -