TY  - JOUR
PY  - 2022//
TI  - Clozapine reduces recurrent suicidal and self-injurious behavior in treatment-refractory incarcerated individuals
JO  - Journal of correctional health care
A1  - Zarzar, Theodore R.
A1  - Rosen, David L.
A1  - Mayo, James P.
A1  - O'Connell, Maria G.
A1  - Catlett, Terri L.
A1  - Reed, John G.
A1  - Williams, Joseph B.
A1  - Sheitman, Brian B.
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - This retrospective review examines clozapine's effects on treatment-refractory incarcerated individuals (N = 23) with recurrent thoughts of self-harm and/or self-injurious behavior. Emergent suicide risk assessments and days on suicide watch were assessed for the 3 months pre- and post-clozapine treatment. Total suicide assessments fell from 73 pre- to 14 post-clozapine, with a median of 2 assessments (interquartile range [IQR]: 1,5) pre-clozapine compared with 0 (IQR: 0,1) post-clozapine (p < 0.0001). Total days on suicide watch decreased from 104 days pre- to 32 post-clozapine, with a median of 3 days (IQR: 0,9) pre-clozapine compared with 0 (IQR: 0,0) post-clozapine (p = 0.0012). Emergency room visits and medical hospitalizations decreased substantially for all months of treatment. Clozapine treatment was associated with marked reductions in self-injurious thoughts and behaviors in high-risk incarcerated individuals.<p />  <p>Language: en</p>
LA  - en
SN  - 1078-3458
UR  - http://dx.doi.org/10.1089/jchc.21.02.0014
ID  - ref1
ER  -