TY - JOUR
PY - 2022//
TI - Cancer and psychiatric diagnoses in the year preceding suicide
JO - Cancer medicine
A1 - Kahn, Geoffrey D.
A1 - Tam, Samantha H.
A1 - Felton, Julia W.
A1 - Westphal, Joslyn
A1 - Simon, Gregory E.
A1 - Owen-Smith, Ashli A.
A1 - Rossom, Rebecca C.
A1 - Beck, Arne L.
A1 - Lynch, Frances L.
A1 - Daida, Yihe G.
A1 - Lu, Christine Y.
A1 - Waring, Stephen
A1 - Frank, Cathrine B.
A1 - Akinyemi, Esther O.
A1 - Ahmedani, Brian K.
SP - ePub
EP - ePub
VL - ePub
IS - ePub
N2 - BACKGROUND: Patients with cancer are known to be at increased risk for suicide but little is known about the interaction between cancer and psychiatric diagnoses, another well-documented risk factor.
METHODS: Electronic medical records from nine healthcare systems participating in the Mental Health Research Network were aggregated to form a retrospective case-control study, with ICD-9 codes used to identify diagnoses in the 1 year prior to death by suicide for cases (N = 3330) or matching index date for controls (N = 297,034). Conditional logistic regression was used to assess differences in cancer and psychiatric diagnoses between cases and controls, controlling for sex and age.
RESULTS: Among patients without concurrent psychiatric diagnoses, cancer at disease sites with lower average 5-year survival rates were associated with significantly greater relative risk, while cancer disease sites with survival rates of >70% conferred no increased risk. Patients with most psychiatric diagnoses were at higher risk, however, there was no additional risk conferred to these patients by a concurrent cancer diagnosis.
CONCLUSION: We found no evidence of a synergistic effect between cancer and psychiatric diagnoses. However, cancer patients with a concurrent psychiatric illness remain at the highest relative risk for suicide, regardless of cancer disease site, due to strong independent associations between psychiatric diagnoses and suicide. For patients without a concurrent psychiatric illness, cancer disease sites associated with worse prognoses appeared to confer greater suicide risk.
Language: en
LA - en SN - 2045-7634 UR - http://dx.doi.org/10.1002/cam4.5201 ID - ref1 ER -