TY  - JOUR
PY  - 2022//
TI  - Incidence of and factors associated with hyponatremia in traumatic cervical spinal cord injury patients
JO  - Spinal cord series and cases
A1  - Chavasiri, Cholavech
A1  - Suriyachat, Natchaya
A1  - Luksanapruksa, Panya
A1  - Wilartratsami, Sirichai
A1  - Chavasiri, Srinual
SP  - e15
EP  - e15
VL  - 8
IS  - 1
N2  - STUDY DESIGN: Retrospective study. <br><br>OBJECTIVE: To investigate the incidence of and factors associated with hyponatremia among traumatic cervical spinal cord injury (SCI) patients. SETTING: Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand. <br><br>METHODS: This retrospective study included traumatic cervical SCI patients that were admitted to the Siriraj Spinal Unit during January 2002 to May 2013. Patient demographic and clinical data were collected. <br><br>RESULTS: One hundred and twenty-three patients (98 males, 25 females) were enrolled. The mean age of patients was 47.2 ± 16.9 years (range: 11-84). There were 38 complete and 85 incomplete cord injuries. Seventy-six patients were treated surgically, and all others received conservative treatment. Hyponatremia developed in 54 patients (43.9%), and 74.1% of all cases of hyponatremia presented within 9 days after SCI. Hyponatremia occurred on the first day in 10 patients (18.5%), on the fifth day in 6 patients (11.1%), and on the eighth day in 5 patients (9.26%). Hyponatremia occurred in 6/10 patients (60.0%) with upper cervical spine injury (C1-2), and in 48/113 patients (42.5%) with lower cervical spine injury (C3-7) (odds ratio [OR]: 2.031, 95% confidence interval [CI]: 0.543-7.596; p = 0.292). The incidence of hyponatremia was 65.8% in complete SCI patients, and 34.1% in incomplete SCI patients. Logistic regression analysis revealed complete SCI to be the only factor significantly associated with hyponatremia (OR: 3.714, 95% CI: 1.658-8.317; p < 0.001). <br><br>CONCLUSION: Hyponatremia was found to be common in post-traumatic cervical SCI patients. Complete SCI was identified as the only factor significantly associated with hyponatremia in traumatic cervical SCI patients.<p />  <p>Language: en</p>
LA  - en
SN  - 2058-6124
UR  - http://dx.doi.org/10.1038/s41394-022-00475-0
ID  - ref1
ER  -