TY - JOUR PY - 2022// TI - Presence hallucinations during locomotion in patients with Parkinson's disease JO - Movement disorders clinical practice A1 - Potheegadoo, Jevita A1 - Dhanis, Herberto A1 - Horvath, Judit A1 - Burkhard, Pierre R. A1 - Blanke, Olaf SP - 127 EP - 129 VL - 9 IS - 1 N2 - The presence hallucination (PH) is the sensation that somebody is nearby when no one is actually there. Affecting up to 60% of patients with Parkinson's disease (PD) and occurring early, PHs are clinically relevant for indicating potential negative clinical outcome.1-3 Recently, we have induced PHs safely in patients with PD by generating sensorimotor conflicts while patients repeatedly actuated a robotic device providing tactile feedback.4 Patients with symptomatic PHs were more sensitive to such sensorimotor stimulation than those without. We also identified abnormal sensorimotor processes predictive for the occurrence of PHs. Here, we describe the case of two patients with PD who reported PHs after PD onset only when they were involved in repetitive locomotor activities in daily life--clinical evidence in favor of the importance of sensorimotor signals in PHs in PD, compatible with repetitive robotic sensorimotor stimulation inducing PH in PD...

Language: en

LA - en SN - 2330-1619 UR - http://dx.doi.org/10.1002/mdc3.13367 ID - ref1 ER -