TY  - JOUR
PY  - 2007//
TI  - Ciguatera poisoning
JO  - Practical neurology
A1  - Achaibar, Kira C.
A1  - Moore, S.
A1  - Bain, Peter G.
SP  - 316
EP  - 322
VL  - 7
IS  - 5
N2  - Ciguatera is a form of poisoning that occurs after eating tropical and subtropical ciguatoxic fish. The ciguatoxins are a family of heat stable, lipid soluble cyclic polyether compounds that bind to and open voltage-sensitive Na(+) channels at resting membrane potential, resulting in neural hyperexcitability, as well as swelling of the nodes of Ranvier. The authors describe a 45-year-old man who developed acute gastrointestinal symptoms in Antigua soon after eating red snapper and grouper, potentially "ciguatoxic fish". This was followed by neurological symptoms 24-48 hours later, including temperature reversal (paradoxical dysaesthesia), intense pruritus and increased nociception as a result of a small fibre peripheral neuropathy. The patient's symptoms and small fibre neuropathy improved over a period of 10 months.<p />  <p>Language: en</p>
LA  - en
SN  - 1474-7758
UR  - http://dx.doi.org/10.1136/jnnp.2007.129049
ID  - ref1
ER  -