TY  - JOUR
PY  - 2021//
TI  - Frequent interpersonal stress and inflammatory reactivity predict depressive-symptom increases: two tests of the social-signal-transduction theory of depression
JO  - Psychological science
A1  - Madison, Annelise A.
A1  - Andridge, Rebecca
A1  - Shrout, M. Rosie
A1  - Renna, Megan E.
A1  - Bennett, Jeanette M.
A1  - Jaremka, Lisa M.
A1  - Fagundes, Christopher P.
A1  - Belury, Martha A.
A1  - Malarkey, William B.
A1  - Kiecolt-Glaser, Janice K.
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - The social-signal-transduction theory of depression asserts that people who experience ongoing interpersonal stressors and mount a greater inflammatory response to social stress are at higher risk for depression. The current study tested this theory in two adult samples. In Study 1, physically healthy adults (N = 76) who reported more frequent interpersonal tension had heightened depressive symptoms at Visit 2, but only if they had greater inflammatory reactivity to a marital conflict at Visit 1. Similarly, in Study 2, depressive symptoms increased among lonelier and less socially supported breast-cancer survivors (N = 79). This effect was most pronounced among participants with higher inflammatory reactivity to a social-evaluative stressor at Visit 1. In both studies, noninterpersonal stress did not interact with inflammatory reactivity to predict later depressive symptoms.<p />  <p>Language: en</p>
LA  - en
SN  - 0956-7976
UR  - http://dx.doi.org/10.1177/09567976211031225
ID  - ref1
ER  -