TY  - JOUR
PY  - 2018//
TI  - Different patterns of orthostatic hypotension in older patients with unexplained falls or syncope: orthostatic hypotension patterns in older people
JO  - European geriatric medicine
A1  - Roosendaal, Elizabeth J.
A1  - Moeskops, Simone J.
A1  - Germans, Tjeerd
A1  - Ruiter, Jaap H.
A1  - Jansen, René W. M. M.
SP  - 485
EP  - 492
VL  - 9
IS  - 4
N2  - PURPOSE: To evaluate different patterns of orthostatic hypotension (OH) and its relation to mortality in older patients with unexplained falls or syncope. <br><br>METHODS: This is an observational cohort study in consecutive patients aged ≥ 65 years with unexplained falls or syncope at a Fall Syncope day clinic November 2011 until May 2016. OH is defined as a decrease in systolic blood pressure (BP) ≥ 20 mmHg and/or in diastolic BP ≥ 10 mmHg during standing test. Main outcomes are the baseline characteristics and prevalence of patients with classical OH (decrease BP until 3 min), delayed OH (decrease of BP from 5 to 10 min) and continuous OH (decrease of BP for 10 min). Secondary outcome is the relation between different OH patterns and mortality. <br><br>RESULTS: Of 374 patients with a mean age of 80 year (SD 6.6), 56% of the patients had OH: 16% had classical OH, 8% delayed OH, 32% had continuous OH and 44% had no OH. Patients with continuous OH and patients with delayed OH tended to have a higher mortality compared to patients with classical OH, 14 vs. 5% (P = 0.07) and 17 vs. 5% (P = 0.06). This possible relation between OH patterns and mortality could not be confirmed in multivariate analysis. <br><br>CONCLUSIONS: In these very old patients, there are various patterns of decline in standing BP. Delayed and continuous OH will be missed if BP is measured only for 3 min during standing. This is important because patients with continuous OH and delayed OH might have a relation with mortality. Our results encourage additional studies investigating the relation between different OH patterns and mortality.<p />  <p>Language: en</p>
LA  - en
SN  - 1878-7649
UR  - http://dx.doi.org/10.1007/s41999-018-0063-1
ID  - ref1
ER  -