TY  - JOUR
PY  - 2021//
TI  - Variations in seasonal solar insolation are associated with a history of suicide attempts in bipolar I disorder
JO  - International journal of bipolar disorders
A1  - Dodd, Seetal
A1  - Desai, Pratikkumar
A1  - Castro, Angela Marianne Paredes
A1  - Cappucciati, Marco
A1  - Del Zompo, Maria
A1  - Bauer, Michael
A1  - Baethge, Christopher
A1  - Ayhan, Yavuz
A1  - Aydın, Memduha
A1  - Benedetti, Francesco
A1  - Belmaker, Robert H.
A1  - Belizario, Gabriel Okawa
A1  - Belete, Tilahun
A1  - Altınbaş, Kursat
A1  - Glenn, Tasha
A1  - Vares, Edgar Arrua
A1  - Ardau, Raffaella
A1  - Angelopoulos, Elias
A1  - Andreassen, Ole A.
A1  - Belete, Habte
A1  - Behere, Prakash B.
A1  - Behere, Aniruddh P.
A1  - Becerra-Palars, Claudia
A1  - Balaban, Ceylan
A1  - Baune, Bernhard T.
A1  - Cabrera, Jorge
A1  - Berk, Michael
A1  - Cheung, Eric Y. Wo
A1  - Chen, Wei-Ling
A1  - Crowe, Marie
A1  - Chiesa, Silvia
A1  - Dallaspezia, Sara
A1  - Cuomo, Alessandro
A1  - Agaoglu, Esen
A1  - Alda, Martin
A1  - Achtyes, Eric D.
A1  - Brady, Conan
A1  - Bauer, Rita
A1  - Bellivier, Frank
A1  - Bjella, Thomas D.
A1  - Birabwa-Oketcho, Harriet
A1  - Bicakci, Şule
A1  - Bersudsky, Yuly
A1  - Donix, Markus
A1  - Etain, Bruno
A1  - Fagiolini, Andrea
A1  - Fellendorf, Frederike T.
A1  - Ferensztajn-Rochowiak, Ewa
A1  - Fiedorowicz, Jess G.
A1  - Fountoulakis, Kostas N.
A1  - Frye, Mark A.
A1  - Geoffroy, Pierre A.
A1  - Gonzalez-Pinto, Ana
A1  - Gottlieb, John F.
A1  - Grof, Paul
A1  - Haarman, Bartholomeus C. M.
A1  - Harima, Hirohiko
A1  - Hasse-Sousa, Mathias
A1  - Henry, Chantal
A1  - Høffding, Lone
A1  - Houenou, Josselin
A1  - Imbesi, Massimiliano
A1  - Isometsä, Erkki T.
A1  - Ivković, Maja
A1  - Janno, Sven
A1  - Johnsen, Simon
A1  - Kapczinski, Flavio
A1  - Karakatsoulis, Gregory N.
A1  - Kardell, Mathias
A1  - Kessing, Lars Vedel
A1  - Kim, Seong Jae
A1  - König, Barbara
A1  - Kot, Timur L.
A1  - Koval, Michael
A1  - Kunz, Mauricio
A1  - Lafer, Beny
A1  - Landén, Mikael
A1  - Larsen, Erik R.
A1  - Lenger, Melanie
A1  - Lewitzka, Ute
A1  - Licht, Rasmus W.
A1  - Lopez-Jaramillo, Carlos
A1  - MacKenzie, Alan
A1  - Madsen, Helle Østergaard
A1  - Madsen, Simone Alberte Kongstad A.
A1  - Mahadevan, Jayant
A1  - Mahardika, Agustine
A1  - Manchia, Mirko
A1  - Marsh, Wendy
A1  - Martinez-Cengotitabengoa, Mónica
A1  - Martiny, Klaus
A1  - Mashima, Yuki
A1  - McLoughlin, Declan M.
A1  - Meesters, Ybe
A1  - Melle, Ingrid
A1  - Meza-Urzúa, Fátima
A1  - Ming, Mok Yee
A1  - Monteith, Scott
A1  - Moorthy, Muthukumaran
A1  - Morken, Gunnar
A1  - Mosca, Enrica
A1  - Mozzhegorov, Anton A.
A1  - Munoz, Rodrigo
A1  - Mythri, Starlin V.
A1  - Nacef, Fethi
A1  - Nadella, Ravi K.
A1  - Nakanotani, Takako
A1  - Nielsen, René Ernst
A1  - O'Donovan, Claire
A1  - Omrani, Adel
A1  - Osher, Yamima
A1  - Ouali, Uta
A1  - Pantović-Stefanović, Maja
A1  - Pariwatcharakul, Pornjira
A1  - Petite, Joanne
A1  - Pfennig, Andrea
A1  - Ruiz, Yolanda Pica
A1  - Pilhatsch, Maximilian
A1  - Pinna, Marco
A1  - Pompili, Maurizio
A1  - Porter, Richard
A1  - Quiroz, Danilo
A1  - Rabelo-da-Ponte, Francisco Diego
A1  - Ramesar, Raj
A1  - Rasgon, Natalie
A1  - Ratta-Apha, Woraphat
A1  - Ratzenhofer, Michaela
A1  - Redahan, Maria
A1  - Reddy, M. S.
A1  - Reif, Andreas
A1  - Reininghaus, Eva Z.
A1  - Richards, Jenny Gringer
A1  - Ritter, Philipp
A1  - Rybakowski, Janusz K.
A1  - Sathyaputri, Leela
A1  - Scippa, Ângela M.
A1  - Simhandl, Christian
A1  - Severus, Emanuel
A1  - Smith, Daniel
A1  - Smith, José
A1  - Stackhouse, Paul W. Jr
A1  - Stein, Dan J.
A1  - Stilwell, Kellen
A1  - Strejilevich, Sergio
A1  - Su, Kuan-Pin
A1  - Subramaniam, Mythily
A1  - Sulaiman, Ahmad Hatim
A1  - Suominen, Kirsi
A1  - Tanra, Andi J.
A1  - Tatebayashi, Yoshitaka
A1  - Teh, Wen Lin
A1  - Tondo, Leonardo
A1  - Torrent, Carla
A1  - Tuinstra, Daniel
A1  - Uchida, Takahito
A1  - Vaaler, Arne E.
A1  - Veeh, Julia
A1  - Vieta, Eduard
A1  - Viswanath, Biju
A1  - Yoldi-Negrete, Maria
A1  - Yalcinkaya, Oguz Kaan
A1  - Young, Allan H.
A1  - Zgueb, Yosra
A1  - Whybrow, Peter C.
SP  - e26
EP  - e26
VL  - 9
IS  - 1
N2  - BACKGROUND: Bipolar disorder is associated with circadian disruption and a high risk of suicidal behavior. In a previous exploratory study of patients with bipolar I disorder, we found that a history of suicide attempts was associated with differences between winter and summer levels of solar insolation. The purpose of this study was to confirm this finding using international data from 42% more collection sites and 25% more countries. <br><br>METHODS: Data analyzed were from 71 prior and new collection sites in 40 countries at a wide range of latitudes. The analysis included 4876 patients with bipolar I disorder, 45% more data than previously analyzed. Of the patients, 1496 (30.7%) had a history of suicide attempt. Solar insolation data, the amount of the sun's electromagnetic energy striking the surface of the earth, was obtained for each onset location (479 locations in 64 countries). <br><br>RESULTS: This analysis confirmed the results of the exploratory study with the same best model and slightly better statistical significance. There was a significant inverse association between a history of suicide attempts and the ratio of mean winter insolation to mean summer insolation (mean winter insolation/mean summer insolation). This ratio is largest near the equator which has little change in solar insolation over the year, and smallest near the poles where the winter insolation is very small compared to the summer insolation. Other variables in the model associated with an increased risk of suicide attempts were a history of alcohol or substance abuse, female gender, and younger birth cohort. The winter/summer insolation ratio was also replaced with the ratio of minimum mean monthly insolation to the maximum mean monthly insolation to accommodate insolation patterns in the tropics, and nearly identical results were found. All estimated coefficients were significant at p < 0.01. <br><br>CONCLUSION: A large change in solar insolation, both between winter and summer and between the minimum and maximum monthly values, may increase the risk of suicide attempts in bipolar I disorder. With frequent circadian rhythm dysfunction and suicidal behavior in bipolar disorder, greater understanding of the optimal roles of daylight and electric lighting in circadian entrainment is needed.<p />  <p>Language: en</p>
LA  - en
SN  - 2194-7511
UR  - http://dx.doi.org/10.1186/s40345-021-00231-7
ID  - ref1
ER  -