TY - JOUR PY - 2021// TI - Eating disorders and suicidal behaviors in adolescents with major depression: insights from the US hospitals JO - Behavioral sciences (Basel, Switzerland) A1 - Patel, Rikinkumar S. A1 - Machado, Tanya A1 - Tankersley, William E. SP - EP - VL - 11 IS - 5 N2 - OBJECTIVE: To evaluate the odds of association between suicidal ideation and/or attempt with comorbid eating disorders in adolescents with major depressive disorder (MDD).

METHODS: We conducted a cross-sectional study and included 122,020 adolescents with a primary diagnosis of MDD from the nationwide inpatient sample (NIS, 2012-2014). They were sub-grouped by a comorbid diagnosis of eating disorders (N = 1675). We calculated the adjusted odds ratio (aOR) using a logistic regression model with demographic confounders for associations of eating disorders with suicidal ideation and attempt.

RESULTS: Suicidal ideations were seen in a higher proportion of adolescents with eating disorders (46.3% vs. 14.2% in those without eating disorders). On the contrary, a low proportion of adolescents with eating disorders had suicidal attempts (0.9% vs. 39.4% in those without eating disorders). Overall, eating disorders were associated with higher odds for suicidal ideations (aOR 5.36, 95% CI 4.82-5.97) compared to those without eating disorders, but with lower odds of suicidal attempt (aOR 0.02, 95% CI 0.01-0.03).

CONCLUSIONS: Adolescents with MDD and comorbid eating disorders had five-times increased odds of suicidal ideations but lower odds of a suicide attempt. Self-harm/injurious behaviors are early signs of suicidal ideations in these patients. A collaborative care model is required for the screening, early diagnosis, and management of adolescents with eating disorders to improve their quality of life.

Language: en

LA - en SN - 2076-328X UR - http://dx.doi.org/10.3390/bs11050078 ID - ref1 ER -