TY  - JOUR
PY  - 2021//
TI  - Continuous venovenous hemofiltration as a rescue therapy for severe acetaminophen toxicity in a toddler
JO  - Journal of pediatric intensive care
A1  - Awasthi, Puspraj
A1  - Jindal, Ankush
A1  - Sharma, Yogish
A1  - Williams, Vijai
A1  - Ravikumar, Namita
A1  - Nallasamy, Karthi
A1  - Angurana, Suresh Kumar
SP  - 159
EP  - 161
VL  - 10
IS  - 2
N2  - Acetaminophen poisoning is one of the common accidental poisoning in children. Accidental administration of mismatched doses of drops for syrups can lead to life-threatening overdose. N-acetylcysteine (NAC) is the specific antidote; however, extracorporeal therapy such as continuous venovenous hemofiltration (CVVH) can be used as a rescue measure when there is no improvement despite adequate NAC therapy and can be lifesaving. We reported an 18-month-old male infant patient who presented with acetaminophen poisoning following accidental ingestion of acetaminophen drops in place of syrup and developed fulminant hepatic failure. Treatment with NAC did not lead to improvement and CVVH was used as a rescue therapy for 24 hours which led to dramatic clinical and biochemical improvement with intact neurological outcome.<p />  <p>Language: en</p>
LA  - en
SN  - 2146-4618
UR  - http://dx.doi.org/10.1055/s-0040-1712158
ID  - ref1
ER  -