TY  - JOUR
PY  - 2021//
TI  - Neuroinflammation and hypothalamo-pituitary dysfunction: focus of traumatic brain injury
JO  - International journal of molecular sciences
A1  - Mele, Chiara
A1  - Pingue, Valeria
A1  - Caputo, Marina
A1  - Zavattaro, Marco
A1  - Pagano, Loredana
A1  - Prodam, Flavia
A1  - Nardone, Antonio
A1  - Aimaretti, Gianluca
A1  - Marzullo, Paolo
SP  - 
EP  - 
VL  - 22
IS  - 5
N2  - The incidence of traumatic brain injury (TBI) has increased over the last years with an important impact on public health. Many preclinical and clinical studies identified multiple and heterogeneous TBI-related pathophysiological mechanisms that are responsible for functional, cognitive, and behavioral alterations. Recent evidence has suggested that post-TBI neuroinflammation is responsible for several long-term clinical consequences, including hypopituitarism. This review aims to summarize current evidence on TBI-induced neuroinflammation and its potential role in determining hypothalamic-pituitary dysfunctions.<p />  <p>Language: en</p>
LA  - en
SN  - 1661-6596
UR  - http://dx.doi.org/10.3390/ijms22052686
ID  - ref1
ER  -