TY  - JOUR
PY  - 2021//
TI  - Risk factors for suicidal tendency in people with epilepsy in China: a case-control study
JO  - Scientific reports
A1  - Lin, Mintao
A1  - Chen, Jiani
A1  - Li, Sisi
A1  - Qin, Yingjie
A1  - Wang, Xuruan
A1  - Liu, Yadong
A1  - Abdulaziz, Ammar Taha Abdullah
A1  - Liu, Wenyu
A1  - Zhou, Dong
A1  - Li, Jinmei
SP  - e2742
EP  - e2742
VL  - 11
IS  - 1
N2  - People with epilepsy (PWE) have an increased suicide prevalence. This study aimed to identify the risk factors for suicidal tendency among PWE in West China. A nested case-control study was designed in a cohort of patients with epilepsy (n = 2087). In total, 28 variates were calculated. In the univariate analysis, unemployment, low income, seizure frequency, seizure-free time, infectious or structural etiology, levetiracetam or phenobarbital use, anxiety, depression, and stigma were associated with suicidal tendency. A multivariate analysis indicated that unemployment (odds ratio [OR] 5.74, 95% confidence interval [CI] 2.13-15.48), levetiracetam use (OR 2.80, 95%CI 1.11-7.05), depression (C-NDDI-E score ≥ 13; OR 3.21, 95%CI 1.26-8.21), and stigma (SSCI score ≥ 16; OR 6.67, 95%CI 1.80-24.69) were independently associated with suicidal tendency. Conditional inference tree analysis indicated that SSCI and C-NDDI-E scores could effectively identify patients with suicidal tendency. Thus, this study suggests that unemployment, levetiracetam use, depression, and stigma are independent risk factors for suicidal tendency in PWE in China.<p />  <p>Language: en</p>
LA  - en
SN  - 2045-2322
UR  - http://dx.doi.org/10.1038/s41598-021-81870-9
ID  - ref1
ER  -