TY  - JOUR
PY  - 2020//
TI  - Unintentional ethylene glycol poisoning in an adolescent
JO  - Curēus
A1  - Patel, Rutul
A1  - Mistry, Anuja Mahesh
A1  - Mistry, Chandrika M.
SP  - e11521
EP  - e11521
VL  - 12
IS  - 11
N2  - The differential diagnosis is broad when a patient presents with an altered mental  status. Ethylene glycol poisoning, a life-threatening condition, can occur as an  intentional self-harm attempt or unintentional consumption. It is metabolized in the  liver by a series of enzymes, and the metabolites so formed are responsible for the  majority of clinical effects. The diverse range of clinical effects includes central  nervous system (CNS), gastrointestinal, cardiovascular system (CVS), pulmonary as  well as renal effects. The evidence of metabolic acidosis, elevated anion gap, high  osmolal gap, and calcium oxalate crystals in laboratory analysis strongly suggests  ethylene glycol poisoning. The treatment traditionally consists of alcohol  dehydrogenase inhibitors such as fomepizole or ethanol, and in some cases,  hemodialysis is needed as well.<p />  <p>Language: en</p>
LA  - en
SN  - 2168-8184
UR  - http://dx.doi.org/10.7759/cureus.11521
ID  - ref1
ER  -