TY  - JOUR
PY  - 2020//
TI  - Prognosis after mild traumatic brain injury: influence of psychiatric disorders
JO  - Brain sciences
A1  - Marinkovic, Ivan
A1  - Isokuortti, Harri
A1  - Huovinen, Antti
A1  - Trpeska Marinkovic, Daniela
A1  - Mäki, Kaisa
A1  - Nybo, Taina
A1  - Korvenoja, Antti
A1  - Rahul, Raj
A1  - Vataja, Risto
A1  - Melkas, Susanna
SP  - e916
EP  - e916
VL  - 10
IS  - 12
N2  - BACKGROUND: We evaluated the prevalence of psychiatric disorders in mild traumatic  brain injury (MTBI) patients and investigated psychiatric comorbidity in relation to  subjective symptoms and return to work (RTW). <br><br>METHODS: We recruited 103 MTBI  patients (mean age 40.8 years, SD 3.1) prospectively from University Hospital. The  patients were followed up for one year. The Rivermead Post-Concussion Symptom  Questionnaire (RPQ) and Extended Glasgow Outcome Scale (GOSE) were administered one  month after MTBI. Three months after MTBI, any psychiatric disorders were assessed  using the Structured Clinical Interview for DSM-IV Axis I Disorders. <br><br>RESULTS:  Psychiatric disorders were diagnosed in 26 patients (25.2%). The most common  disorders were previous/current depression. At three months, there was no difference  between patients with psychiatric disorders versus those without them in RTW (95.7%  vs. 87.3%, p = 0.260) or at least in part-time work (100% vs. 94.4%, p = 0.245). In  Kaplan-Meier analysis, the median time to RTW was 10 days for both groups. The  median RPQ score was 13.0 (Interquartile range (IQR) 6.5-19.0) in patients with a  psychiatric disorder compared to 8.5 (IQR 2.3-14.0) in those without one (p =  0.021); respectively, the median GOSE was 7.0 (IQR 7.0-8.0) compared to 8.0 (IQR  7.0-8.0, p = 0.003). <br><br>CONCLUSIONS: Approximately every fourth patient with MTBI had a  psychiatric disorder. These patients reported more symptoms, and their functional  outcome measured with GOSE at one month after MTBI was worse. However, presence of  any psychiatric disorder did not affect RTW. Early contact and adequate follow-up  are important when supporting the patient's return to work.<p />  <p>Language: en</p>
LA  - en
SN  - 2076-3425
UR  - http://dx.doi.org/10.3390/brainsci10120916
ID  - ref1
ER  -