TY  - JOUR
PY  - 2020//
TI  - Psychosocial and trauma-related stress and risk of dementia: a meta-analytic systematic review of longitudinal studies
JO  - Journal of geriatric psychiatry and neurology
A1  - Bougea, Anastasia
A1  - Anagnostouli, Maria
A1  - Angelopoulou, Efthalia
A1  - Spanou, Ioanna
A1  - Chrousos, George
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - Stress has deleterious effects on brain health and yet, the prognostic value of psychosocial stress regarding the most common types of dementias, including Alzheimer disease, is still unclear. The primary aim of this systematic review was to explore the association between psychosocial stress and late onset dementia. We classified 24articles from Medline, PsycINFO, CINAHL, and Web of Science, as pertaining toxic categories of psychosocial and trauma-related stress (low socio-economic status [SES] related inequalities, marital status, posttraumatic stress disorder, work stress, "vital exhaustion" [VE], and, combined stressors). Using the Quality of Prognosis Studies in Systematic Reviews tool, we judged the quality of evidence to be low. This systematic review provided some non-robust, yet suggestive evidence that the above psychosocial types of stress are associated with increased risk of dementia in later life. Future robust, longitudinal studies with repeated validated measures of psychosocial stress and dementiaare required to strengthen or refute these findings.<p />  <p>Language: en</p>
LA  - en
SN  - 0891-9887
UR  - http://dx.doi.org/10.1177/0891988720973759
ID  - ref1
ER  -