TY  - JOUR
PY  - 2020//
TI  - Hyperbaric oxygen for severe traumatic brain injury: a randomized trial
JO  - Journal of international medical research
A1  - Zhong, Xianliang
A1  - Shan, Aijun
A1  - Xu, Jianzhong
A1  - Liang, Jian
A1  - Long, Ying
A1  - Du, Bo
SP  - e300060520939824
EP  - e300060520939824
VL  - 48
IS  - 10
N2  - OBJECTIVE: The present study aimed to explore the effects of hyperbaric oxygen therapy on the prognosis and neurological function of patients with severe traumatic brain injury.     METHODS: A prospective study was carried out in 88 patients diagnosed with severe brain injury at our hospital and they were enrolled as research participants and randomly assigned to control and experimental groups (n = 44 per group) using a random number table method. Both groups underwent routine treatment. Patients in the experimental group were administered hyperbaric oxygen therapy approximately 1 week after admission when their vital signs had stabilized.     RESULTS: No significant intergroup differences were observed in the Glasgow Coma Scale (GCS) and U.S. National Institutes of Health Stroke Scale (NIHSS) scores before treatment. However, after oxygen treatment, compared with the control group, the experimental group showed higher GCS and lower NIHSS scores. The GCS score at admission, tracheotomy status, and first hyperbaric oxygen therapy duration were independent prognostic factors in patients with severe traumatic brain injury.     CONCLUSION: Hyperbaric oxygen therapy may promote recovery of neurological function and improve the cognitive function and prognosis of patients with severe traumatic brain injury.<p />  <p>Language: en</p>
LA  - en
SN  - 0300-0605
UR  - http://dx.doi.org/10.1177/0300060520939824
ID  - ref1
ER  -