TY  - JOUR
PY  - 2020//
TI  - Economic evaluation of intrahospital clinical practices in injury care: protocol for a 10-year systematic review
JO  - BMJ open
A1  - Conombo, Blanchard
A1  - Guertin, Jason Robert
A1  - Tardif, Pier-Alexandre
A1  - Farhat, Imen
A1  - Moore, Thomas
A1  - Bouderba, Samy
A1  - Soltana, Kahina
A1  - Archambault, Patrick
A1  - Berthelot, Simon
A1  - Lauzier, François
A1  - Turgeon, Alexis F.
A1  - Stelfox, Henry Thomas
A1  - Chassé, Michael
A1  - Hoch, Jeffrey
A1  - Moore, Lynne
SP  - e034472
EP  - e034472
VL  - 10
IS  - 7
N2  - INTRODUCTION: Underuse of high-value clinical practices and overuse of low-value practices are major sources of inefficiencies in modern healthcare systems. Injuries are second only to cardiovascular disease in terms of acute care costs but data on the economic impact of clinical practices for injury admissions are lacking. This study aims to summarise evidence on the economic value of intrahospital clinical practices for injury care.     METHODS AND ANALYSIS: We will perform a systematic review to identify research articles in economic evaluation of intrahospital clinical practices in acute injury care. We will search MEDLINE and databases such as Embase, Web of Science, NHS Economic Evaluation Database, Cochrane CENTRAL, BIOSIS and CINAHL for randomised or non-randomised controlled trials and observational studies using a combination of keywords and controlled vocabulary. We will consider the following outcomes relative to economic evaluations: incremental cost-effectiveness ratio, incremental cost-utility ratio, incremental net health benefit, incremental net monetary benefit (iNMB) and incremental cost-benefit ratio. Pairs of independent reviewers will evaluate studies that meet eligibility criteria and extract data from included articles using an electronic data extraction form. All outcomes will be converted into iNMB. We will report iNMB for practices classified by type of practice (hospitalisation, consultation, diagnostic, therapeutic-surgical, therapeutic-drugs, therapeutic-other). <br><br>RESULTS obtained with a ceiling ratio of $50 000 per quality-adjusted life year gained for identified clinical practices will be summarised by charting forest plots. In line with Cochrane recommendations for systematic reviews of economic evaluations, meta-analyses will not be conducted.     ETHICS AND DISSEMINATION: Ethics approval is not required as original data will not be collected. This study will summarise existing evidence on the economic value of clinical practices in injury care. <br><br>RESULTS will be used to advance knowledge on value-based care for injury admissions and will be disseminated through a peer-reviewed article, international scientific meetings and clinical and healthcare quality associations.<p />  <p>Language: en</p>
LA  - en
SN  - 2044-6055
UR  - http://dx.doi.org/10.1136/bmjopen-2019-034472
ID  - ref1
ER  -