TY  - JOUR
PY  - 2020//
TI  - Epidemiology of fatal/non-fatal suicide among patients with chronic osteomyelitis (COM): a nationwide population-based study
JO  - Journal of international medical research
A1  - Hung, Chih-Hung
A1  - Ko, Jih-Yang
A1  - Liao, Pei-Shao
A1  - Yeh, Chen-Wei
A1  - Hsu, Chieh-Cheng
A1  - Lin, Mei-Chen
A1  - Hsu, Horng-Chaung
A1  - Kuo, Shu-Jui
SP  - e300060520919238
EP  - e300060520919238
VL  - 48
IS  - 6
N2  - OBJECTIVE: Chronic osteomyelitis (COM) can induce systemic inflammation, and systemic inflammation may be associated with suicide tendency. However, no studies have investigated the correlation between COM and suicide tendency.     METHODS: The aim of this population-based study was to determine the epidemiology of fatal/non-fatal suicide among COM patients. Subjects with at least two outpatient visits or one course of inpatient care diagnosed with COM were recruited into a COM cohort. The control/COM subject ratio was approximately 4:1 matched by age, sex, major depression coding and index year (COM patients). Subjects with suicide attempts before COM diagnosis and subjects aged <20 years were excluded.     RESULTS: COM patients had 1.93 (95% confidence interval [CI]: 1.11-3.36) times the risk of fatal/non-fatal suicide as control subjects. Considering death as the competing event of fatal/non-fatal suicide, COM patients had 1.76 (95% CI: 1.03-3.01) times the risk of fatal/non-fatal suicide (competing risk regression model). The effect of COM on fatal/non-fatal suicide was more prominent among diabetic patients. COM severity also correlated with the risk of fatal/non-fatal suicide.     CONCLUSIONS: More attention must be paid to suicide tendency among COM patients.<p />  <p>Language: en</p>
LA  - en
SN  - 0300-0605
UR  - http://dx.doi.org/10.1177/0300060520919238
ID  - ref1
ER  -