TY - JOUR PY - 2020// TI - The impact of obstructive sleep apnoea on balance, gait and falls risk: a narrative review of the literature JO - Journals of gerontology. Series A: Biological sciences and medical sciences A1 - Stevens, David A1 - Jackson, Brianna A1 - Carberry, Jayne A1 - McLoughlin, James A1 - Barr, Chris A1 - Mukherjee, Sutapa A1 - Oh, Aaron A1 - McEvoy, R. Doug A1 - Crotty, Maria A1 - Vakulin, Andrew SP - ePub EP - ePub VL - ePub IS - ePub N2 - Falls related hospitalisation and injury rates are steadily increasing globally due to a growth in the aging population, and the associated health problems that increase risk of falls. One such associated health problem is sleep disturbances and disorders. Recent cohort studies have shown that subjectively reported poor quality sleep is associated with an increased risk of falls. Obstructive sleep apnoea (OSA) is a common sleep disorder characterised by the repetitive reductions, or cessation, of airflow. Some studies have shown that OSA impairs posture/balance and gait with nocturnal hypoxemia the likely main cause. Emerging evidence suggests that treating OSA by continuous positive airway pressure (CPAP) can improve gait, but no studies to date have examined the effect of CPAP on posture/balance. The overall control of balance relies on a complex interaction between several physiological functions including vestibular, muscle, visual and cognitive functions. We postulate that OSA impacts balance by affecting these different systems to various degrees, with the nocturnal hypoxic burden likely playing an important role. Importantly, these impairments in balance/posture and possible falls risk may be alleviated by OSA treatment. Larger mechanistic studies are needed to properly elucidate how OSA affects falls risk and future large-scale randomised control trials are needed to determine the effectiveness of OSA treatment in reducing the risk of falls.

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Language: en

LA - en SN - 1079-5006 UR - http://dx.doi.org/10.1093/gerona/glaa014 ID - ref1 ER -