TY  - JOUR
PY  - 2020//
TI  - Relation between low pulmonary function and skeletal muscle index in burn patients with major burn injury and smoke inhalation: a retrospective study
JO  - Journal of burn care and research
A1  - Won, Yu Hui
A1  - Cho, Yoon Soo
A1  - Kim, Dong Hyun
A1  - Joo, So Young
A1  - Seo, Cheong Hoon
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - This report is to evaluate the relation between pulmonary function, respiratory muscle strength and skeletal muscle index (SMI) in patients with major burn injury and smoke inhalation. A total of 54 inhalation burn patients were analyzed. Appendicular skeletal muscle mass (ASM) is a sum of the muscle mass of both arms and legs. SMI is adjusting for body size using body mass index (ASM/BMI). Spirometry was performed to evaluate pulmonary function. Pulmonary function tests included peak cough flow (PCF), forced vital capacity (FVC), 1-second forced expiratory volume (FEV1), forced expiratory flow rate between 25% and 75% of the FVC (FEF 25-75), FEV1/FVC ratio expressed as a percentage (FEV1/FVC %), peak expiratory flow (PEF), and maximum voluntary ventilation (MVV). Expiratory and inspiratory muscle strengths were measured. The relations between pulmonary function, respiratory muscle strength and SMI were investigated. SMI showed significant correlations with PCF (r=0.34 and p=0.02), FVC (r=0.55 and p < 0.001), FEV1 (r=0.45 and p=0.001), PEF (r=0.35 and p=0.01). In multiple regression analysis including age, TBSA, duration of mechanical ventilation, and postburn days studied, SMI was significantly related to FVC, PCF, FEV1, FEV1/FVC, and PEF (p < 0.001, p = 0.02, p = 0.001, p = 0.04 and p = 0.03). Pulmonary function tests are significantly related to SMI in patients with major burn injury and smoke inhalation. Intensive treatment on muscle wasting in patients with burn injury has been proven to be important for improving pulmonary functions.<br><br>© American Burn Association 2020. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.<p />  <p>Language: en</p>
LA  - en
SN  - 1559-047X
UR  - http://dx.doi.org/10.1093/jbcr/iraa015
ID  - ref1
ER  -