TY  - JOUR
PY  - 2020//
TI  - Quality of life after caustic ingestion
JO  - Annals of surgery
A1  - Faron, Matthieu
A1  - Corte, Helene
A1  - Poghosyan, Tigran
A1  - Bruzzi, Matthieu
A1  - Voron, Thibault
A1  - Sarfati, Emile
A1  - Cattan, Pierre
A1  - Chirica, Mircéa
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - OBJECTIVE: The aim of the study was to evaluate long-term QOL after caustic ingestion. <br><br>BACKGROUND: Caustic ingestion strongly affects patient's QOL but data on the topic is scarce in the literature. <br><br>METHODS: QOL evaluation was conducted in survivors from a large cohort of patients with caustic injuries. QOL was assessed using the EORTC QLQ-OG25 module, the SF12v2 score, and the hospital anxiety and depression scale questionnaire. One hundred thirty-four patients (59 men, median age 43) completed the survey; 72 (54%) patients underwent emergency digestive resection and in 99 (74%) patients underwent esophageal reconstruction. <br><br>RESULTS of QOL questionnaires were compared to average values determined in healthy volunteers and in patients with esophageal cancers. <br><br>RESULTS: The median QLQ-OG25 score was 44 (34, 62) and values were significantly lower when compared to a normal population (P < 0.0001). SF12v2 scores were significantly inferior to those expected in a normal population on both the physical component summary (PCS) (43.3 ± 10.8; P < 0.0001) and the mental component summary (44 ± 9.7; P < 0.0001) scales. Emergency esophageal resection was significantly associated with higher QLQ-OG25 scores (P < 0.0001), but not with mental component summary (P = 0.3), PCS (P = 0.76), HAD anxiety (P = 0.95), and HAD depression scores (P = 0.59); results were similar after extended emergency resection. When compared to esophagocoloplasty alone, pharyngeal reconstruction had a significant negative impact on QLQ-OG25 (P < 0.0001), PCS (P = 0.01), and HAD depression (P = 0.0008) scores. <br><br>CONCLUSIONS: QOL is significantly impaired after caustic ingestion. QOL issues should not influence the emergency surgical strategy but deserve discussion before esophageal reconstruction for caustic injuries.<p />  <p>Language: en</p>
LA  - en
SN  - 0003-4932
UR  - http://dx.doi.org/10.1097/SLA.0000000000003774
ID  - ref1
ER  -