TY  - JOUR
PY  - 2019//
TI  - Perceived change in physical, cognitive, and emotional symptoms after mild traumatic brain injury in patients endorsing pre-injury anxiety or depression
JO  - Journal of neurotrauma
A1  - Karr, Justin Elliott
A1  - Iverson, Grant L.
A1  - Huang, Sheng-Jean
A1  - Silverberg, Noah D.
A1  - Yang, Chi-Cheng
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - The objective of this study was to compare patients with acute-to-subacute MTBI on post-concussion symptom reporting based on whether they retrospectively endorsed experiencing pre-injury anxiety or depression. Patients with MTBI (n=297; 40.4% men; M=38.2 years old, SD=14.0, range=17-65), referred from an emergency department in Taipei, Taiwan, were seen in a neurosurgical outpatient clinic on average 7.7 days since injury (SD=5.7, range=0-21 days), at which time they completed a checklist of post-concussion symptoms. Patients rated their current symptom severity and retrospectively rated their pre-injury symptom severity on 15 physical, cognitive, and emotional symptoms. Patients were grouped based on whether they did or did not endorse mild or greater pre-injury anxiety or depression on this scale. Those endorsing pre-injury anxiety or depression had greater pre-injury (all p's<.001, d range: 0.92-2.03) and post-injury (all p's<.001, d range: 0.65-1.00) symptom severity. However, when analyzing perceived change in symptoms (i.e., post-injury ratings minus pre-injury ratings), only perceived change in cognitive symptoms differed across groups (p=.018, d=0.29), which became non-significant after controlling for gender. Greater post-concussion symptom severity in patients endorsing pre-existing mental health problems may be mostly attributable to elevated symptoms before injury. These findings demonstrate the clinical value of retrospective pre-injury symptom assessment in MTBI management. Greater post-concussion symptom severity in patients with pre-injury mental health problems may represent a continuation of greater pre-injury symptom severity rather than a greater increase in symptom severity after MTBI.<p />  <p>Language: en</p>
LA  - en
SN  - 0897-7151
UR  - http://dx.doi.org/10.1089/neu.2019.6834
ID  - ref1
ER  -