TY - JOUR
PY - 2019//
TI - Psychopharmacology of traumatic brain injury
JO - Handbook of clinical neurology
A1 - Polich, Ginger
A1 - Iaccarino, Mary Alexis
A1 - Zafonte, Ross
SP - 253
EP - 267
VL - 165
IS -
N2 - The pathophysiology of traumatic brain injury (TBI) can be highly variable, involving functional and/or structural damage to multiple neuroanatomical networks and neurotransmitter systems. This wide-ranging potential for physiologic injury is reflected in the diversity of neurobehavioral and neurocognitive symptoms following TBI. Here, we aim to provide a succinct, clinically relevant, up-to-date review on psychopharmacology for the most common sequelae of TBI in the postacute to chronic period. Specifically, treatment for neurobehavioral symptoms (depression, mania, anxiety, agitation/irritability, psychosis, pseudobulbar affect, and apathy) and neurocognitive symptoms (processing speed, attention, memory, executive dysfunction) will be discussed. Treatment recommendations will reflect general clinical practice patterns and the research literature.
Copyright © 2019 Elsevier B.V. All rights reserved.
Language: en
LA - en SN - 0072-9752 UR - http://dx.doi.org/10.1016/B978-0-444-64012-3.00015-0 ID - ref1 ER -