TY  - JOUR
PY  - 2019//
TI  - Functional brain effects of acute concussion in Australian rules football players
JO  - Journal of concussion
A1  - Jackson, Graeme D.
A1  - Makdissi, Michael
A1  - Pedersen, Mangor
A1  - Parker, Donna M.
A1  - Curwood, Evan K.
A1  - Farquharson, Shawna
A1  - Connelly, Alan
A1  - Abbott, David F.
A1  - McCrory, Paul
SP  - e2059700219861200
EP  - e2059700219861200
VL  - 3
IS  - 
N2  - Aim    To determine whether acute sport-related concussion is associated with functional brain changes in Australian rules footballers.     Methods    Twenty acutely concussed professional Australian footballers were studied with 3 T magnetic resonance imaging and compared to 20 age-matched control subjects. We statistically compared whole-brain local functional magnetic resonance imaging connectivity between acutely concussed footballers and controls using voxel-wise permutation testing.     Results    The acutely concussed football players had significantly decreased local functional magnetic resonance imaging connectivity in the right dorsolateral prefrontal cortex, right inferior parietal lobe, and right anterior insula, compared to controls. No functional brain changes between groups within the default mode network were observed.     Discussion    Acutely concussed footballers had in common decreased functional connectivity within the right lateralized "cognitive control network" of the brain that is involved in executive functions, and the "salience network" involved in switching between tasks. Dysfunction of these brain regions is a plausible explanation for typical clinical features of concussion.     Keywords Sport-related concussion, functional magnetic resonance imaging, Australian football, brain connectivity<p />  <p>Language: en</p>
LA  - en
SN  - 2059-7002
UR  - http://dx.doi.org/10.1177/2059700219861200
ID  - ref1
ER  -