TY  - JOUR
PY  - 2019//
TI  - Prediction of long-term quality of life after severe traumatic brain injury based on variables at hospital admission
JO  - Brain injury
A1  - Maillard, Julien
A1  - De Pretto, Michael
A1  - Delhumeau, Cécile
A1  - Walder, Bernhard
SP  - ePub
EP  - ePub
VL  - ePub
IS  - ePub
N2  - <b>Objectives</b>: Variables collected early after severe traumatic brain injury (sTBI) could predict health-related quality of life (HRQoL). Our aim was to determine the prevalence of patients with a low HRQoL 4 years after sTBI and to develop a prediction model including early variables. <b>Methods</b>: Adult patients with both sTBI [abbreviated injury score of the head region (HAIS) >3] and disease-specific HRQoL assessments using the 'Quality of Life after Brain Injury' (QOLIBRI) were included. The outcome was the total score (TS) of QOLIBRI; cutoff for low HRQoL: <60 points. A multivariate logistic regression model and prediction model were performed. <b>Results</b>: One hundred-sixteen patients [median age 50.8 years (IQR 25.9-62.8; 21.6% >65 years)] were included; 68 (58.6%) with HAIS = 4, 48 (41.4%) with HAIS = 5. Median Glasgow Coma Scale (GCS) was 13 (IQR 3-15). Median TS was 77 (IQR 60-88). Low HRQoL was observed in 28 patients (24.1%). Two variables were associated with low HRQoL: GCS <13, working situation other than employed or retired. The prediction model had an AUROC of 0.765; calibration was moderate (Hosmer Lemeshow Chi2 6.82, <i>p</i> = .556). <b>Conclusion</b>: One in four patients had a low HRQoL after 4 years. A lower GCS and working situations were associated with low HRQoL.<p />  <p>Language: en</p>
LA  - en
SN  - 0269-9052
UR  - http://dx.doi.org/10.1080/02699052.2019.1683227
ID  - ref1
ER  -