TY - JOUR PY - 2019// TI - Pulmonary embolism occurring early after major trauma JO - BMJ case reports A1 - Serchan, Paschalitsa A1 - Shorten, George A1 - Maher, Michael A1 - Power, Stephen P. SP - e228783 EP - e228783 VL - 12 IS - 9 N2 - Pulmonary embolism (PE) secondary to trauma is the third most common cause of death in trauma patients who have survived 24 hours following injury. We describe a case of PE diagnosed within 3 hours of a major trauma in a previously well adolescent female. The early occurrence of PE in this case is at odds with what is generally reported (3-5 days) after major trauma. General consensus is that patients who suffer major trauma move from an initial hypocoaguable state, with increased risk of bleeding, to normocoagulable or hypercoaguable state, with a subsequent increased risk of venothromboembolism. However, Sumislawski et al recently demonstrated that a marginally greater proportion of trauma patients were in fact hypercoaguable rather than hypocoaguable on arrival to hospital and that trauma-induced coagulopathy tended to resolve within 24 hours; such data cause us to re-evaluate when to commence thromboprophylaxis for major trauma patients.

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Language: en

LA - en SN - 1757-790X UR - http://dx.doi.org/10.1136/bcr-2018-228783 ID - ref1 ER -