TY  - JOUR
PY  - 2019//
TI  - The association between mental disorders and suicide: a systematic review and meta-analysis of record linkage studies
JO  - Journal of affective disorders
A1  - Too, Lay San
A1  - Spittal, Matthew J.
A1  - Bugeja, Lyndal
A1  - Reifels, Lennart
A1  - Butterworth, Peter
A1  - Pirkis, Jane
SP  - 302
EP  - 313
VL  - 259
IS  - 
N2  - BACKGROUND: There has long been debate about the extent to which mental disorders contribute to suicide. We aimed to examine the evidence on the contribution of mental disorders to suicide among record linkage studies. <br><br>METHODS: We performed a systematic search using eight major health databases for English-language studies published between 1 January 2000 and 11 June 2018 that linked collected data on mental disorders and suicide. We then conducted a meta-analysis to assess risk of suicide conferred by mental disorders. <br><br>RESULTS: Our search identified 20 articles representing 13 unique studies. The pooled rate ratio (RR) was 13.2 (95% CI 8.6-20.3) for psychotic disorders, 12.3 (95% CI 8.9-17.1) for mood disorders, 8.1 (95% CI 4.6-14.2) for personality disorders, 4.4 (95% CI 2.9-6.8) for substance use disorders, and 4.1 (95% CI 2.4-6.9) for anxiety disorders in the general population. The overall pooled RR for these mental disorders was 7.5 (95% CI 6.6-8.6). The population attributable risk of mental disorders was up to 21%. LIMITATIONS: The overall heterogeneity between studies was very high. <br><br>CONCLUSIONS: Our findings underline the important role of mental disorders in suicide. This suggests that ongoing efforts are required to improve access to and quality of mental health care to prevent suicide by people with mental disorders.<br><br>Copyright © 2019 The Authors. Published by Elsevier B.V. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 0165-0327
UR  - http://dx.doi.org/10.1016/j.jad.2019.08.054
ID  - ref1
ER  -