TY  - JOUR
PY  - 2019//
TI  - Interaction between prospective risk factors in the prediction of suicide risk
JO  - Journal of affective disorders
A1  - Grendas, Leandro N.
A1  - Rojas, Sasha M.
A1  - Puppo, Soledad
A1  - Vidjen, Patricia
A1  - Portela, Alicia
A1  - Chiapella, Luciana
A1  - Rodante, Demián E.
A1  - Daray, Federico M.
SP  - 144
EP  - 150
VL  - 258
IS  - 
N2  - BACKGROUND: To meet the goal of preventing suicide the most important thing is to know the risk factors of suicidal behavior and understand their interaction. AIMS: The current study aims to evaluate prospective predictors and the interaction between factors for suicide and suicide re-attempts in high-risk, suicidal patients during a 24 month prospective follow-up period. <br><br>METHODS: A multicenter prospective cohort study was designed to compare data obtained from 324 patients admitted to the emergency department for current suicidal ideation or a recent suicide attempt. Participants were clinically evaluated at baseline and follow-up every 6 months to assess any unfavorable events (suicide or a suicide attempt). To estimate the rate of unfavorable events, the Kaplan-Meier method was used and Cox Proportional Hazards Regression Model was employed to examine predictors of suicide and suicide reattempt. <br><br>RESULTS: The incidence of a new suicide attempt was 26,000 events/100,000 persons-years. The incidence of death by suicide was 1110 events/100,000 person-year. The most reliable predictors of unfavorable events were being women, previous suicide attempts, younger age, and childhood sexual abuse. <br><br>FINDINGS revealed an interaction between childhood sexual abuse and low psychosocial functioning that increased the risk of an unfavorable event. <br><br>CONCLUSION: The risk of suicide re-attempts and suicide in the current 2-year follow-up was high. There was an interaction between low psychosocial functioning and childhood sexual abuse. This evidence should be taken into account for the evaluation and planning of preventive strategies.<br><br>Copyright © 2019 Elsevier B.V. All rights reserved.<p />  <p>Language: en</p>
LA  - en
SN  - 0165-0327
UR  - http://dx.doi.org/10.1016/j.jad.2019.07.071
ID  - ref1
ER  -