TY - JOUR
PY - 2019//
TI - Why exercise may be beneficial in concussion rehabilitation: a cellular perspective
JO - Journal of science and medicine in sport
A1 - Dech, Ryan T.
A1 - Bishop, Scott A.
A1 - Neary, J. Patrick
SP - ePub
EP - ePub
VL - ePub
IS - ePub
N2 - INTRODUCTION: Concussion diagnosis and rehabilitation management has become a prevalent area of research, and yet much is still unknown about these complex injuries. Historically, exercise prescription post-concussion was conservatively used for rehabilitation due to the suspected harmful effects that exercise can have on damaged neurons, and increase in symptoms. However, there has been a shift to implement exercise earlier into recovery as several studies have demonstrated positive outcomes.
OBJECTIVE: The objective of this literature review is to update the reader about new advances in concussion research related to the beneficial effects of physical activity from both a neurometabolic and a broader physiological perspective, using gene expression as a vehicle to demonstrate why and how physical activity has the capacity to optimize recovery from a cellular perspective. To further this clinical guideline, the evidence must continue to support these positive outcomes from an inductive and deductive physiologic approach (i.e., the clinical evidence aligned from a micro- to macroscopic approach and vice versa).
DESIGN: Narrative review.
METHODS: Pubmed and Medline were used with the following key words: concussion and, physical activity, neurometabolic, gene regulation, trauma, nervous system, mild head injury, acute exercise, cellular physiology and pathophysiology.
CONCLUSION: It is our contention that understanding the cellular perspective will help guide clinical management, and promote research into post-concussion exercise.
Copyright © 2019 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved. Language: en
LA - en
SN - 1440-2440
UR - http://dx.doi.org/10.1016/j.jsams.2019.06.007
ID - ref1
ER -