TY - JOUR PY - 2019// TI - Diseases, injuries, and risk factors in child and adolescent health, 1990 to 2017: findings from the Global Burden of Diseases, Injuries, and Risk Factors 2017 Study JO - JAMA pediatrics A1 - Reiner, Robert C. A1 - Olsen, Helen Elizabeth A1 - Ikeda, Chad Thomas A1 - Echko, Michelle M. A1 - Ballestreros, Katherine E. A1 - Manguerra, Helen A1 - Martopullo, Ira A1 - Millear, Anoushka A1 - Shields, Chloe A1 - Smith, Alison A1 - Strub, Bryan A1 - Abebe, Molla A1 - Abebe, Zegeye A1 - Adhena, Beyene Meressa A1 - Adhikari, Tara Ballav A1 - Akibu, Mohammed A1 - Al-Raddadi, Rajaa M. A1 - Alvis-Guzmán, Nelson A1 - Antonio, Carl Abelardo T. A1 - Aremu, Olatunde A1 - Asgedom, Solomon Weldegebreal A1 - Asseffa, Netsanet Abera A1 - Avila-Burgos, Leticia A1 - Barac, Aleksandra A1 - Bärnighausen, Till W. A1 - Bassat, Quique A1 - Benseñor, Isabela M. A1 - Bhutta, Zulfiqar A. A1 - Bijani, Ali A1 - Bililign, Nigus A1 - Cahuana-Hurtado, Lucero A1 - Malta, Deborah Carvalho A1 - Chang, Jung-Chen A1 - Charlson, Fiona J. A1 - Dharmaratne, Samath Dhamminda A1 - Doku, David Teye A1 - Edessa, Dumessa A1 - El-Khatib, Ziad A1 - Erskine, Holly E. A1 - Ferrari, Alize J. A1 - Fullman, Nancy A1 - Gupta, Rahul A1 - Hassen, Hamid Yimam A1 - Hay, Simon I. A1 - Ilesanmi, Olayinka Stephen A1 - Jacobsen, Kathryn H. A1 - Kahsay, Amaha A1 - Kasaeian, Amir A1 - Kassa, Tesfaye Dessale A1 - Kebede, Seifu A1 - Khader, Yousef Saleh A1 - Khan, Ejaz Ahmad A1 - Khan, Mohammed Nuruzzaman A1 - Khang, Young-Ho A1 - Khubchandani, Jagdish A1 - Kinfu, Yohannes A1 - Kochhar, Sonali A1 - Kokubo, Yoshihiro A1 - Koyanagi, Ai A1 - Defo, Barthelemy Kuate A1 - Lal, Dharmesh Kumar A1 - Kumsa, Fekede Asefa A1 - Larson, Heidi J. A1 - Leung, Janni A1 - Mamun, Abdullah A. A1 - Mehata, Suresh A1 - Melku, Mulugeta A1 - Mendoza, Walter A1 - Mezgebe, Haftay Berhane A1 - Miller, Ted R. A1 - Moges, Nurilign Abebe A1 - Mohammed, Shafiu A1 - Mokdad, Ali H. A1 - Monasta, Lorenzo A1 - Neupane, Subas A1 - Nguyen, Huong Lan Thi A1 - Ningrum, Dina Nur Anggraini A1 - Nirayo, Yirga Legesse A1 - Nong, Vuong Minh A1 - Ogbo, Felix Akpojene A1 - Olagunju, Andrew T. A1 - Olusanya, Bolajoko Olubukunola A1 - Olusanya, Jacob Olusegun A1 - Patton, George C. A1 - Pereira, David M. A1 - Pourmalek, Farshad A1 - Qorbani, Mostafa A1 - Rafay, Anwar A1 - Rai, Rajesh Kumar A1 - Ram, Usha A1 - Ranabhat, Chhabi Lal A1 - Renzaho, Andre M. N. A1 - Rezai, Mohammad Sadegh A1 - Ronfani, Luca A1 - Roth, Gregory A. A1 - Safiri, Saeid A1 - Sartorius, Benn A1 - Scott, James G. A1 - Shackelford, Katya Anne A1 - Sliwa, Karen A1 - Sreeramareddy, Chandrashekhar A1 - Sufiyan, Mu'awiyyah Bable A1 - Terkawi, Abdullah Sulieman A1 - Topór-Madry, Roman A1 - Tran, Bach Xuan A1 - Ukwaja, Kingsley Nnanna A1 - Uthman, Olalekan A. A1 - Vollset, Stein Emil A1 - Weldegwergs, Kidu Gidey A1 - Werdecker, Andrea A1 - Whiteford, Harvey A. A1 - Wijeratne, Tissa A1 - Yonemoto, Naohiro A1 - Yotebieng, Marcel A1 - Zuhlke, Liesl J. A1 - Kyu, Hmwe Hmwe A1 - Naghavi, Mohsen A1 - Vos, Theo A1 - Murray, Christopher J. L. A1 - Kassebaum, Nicholas J. SP - e190337 EP - e190337 VL - 173 IS - 6 N2 - IMPORTANCE: Understanding causes and correlates of health loss among children and adolescents can identify areas of success, stagnation, and emerging threats and thereby facilitate effective improvement strategies.

OBJECTIVE: To estimate mortality and morbidity in children and adolescents from 1990 to 2017 by age and sex in 195 countries and territories.

DESIGN, SETTING, AND PARTICIPANTS: This study examined levels, trends, and spatiotemporal patterns of cause-specific mortality and nonfatal health outcomes using standardized approaches to data processing and statistical analysis. It also describes epidemiologic transitions by evaluating historical associations between disease indicators and the Socio-Demographic Index (SDI), a composite indicator of income, educational attainment, and fertility. Data collected from 1990 to 2017 on children and adolescents from birth through 19 years of age in 195 countries and territories were assessed. Data analysis occurred from January 2018 to August 2018.

EXPOSURES: Being under the age of 20 years between 1990 and 2017.

MAIN OUTCOMES AND MEASURES: Death and disability. All-cause and cause-specific deaths, disability-adjusted life years, years of life lost, and years of life lived with disability.

RESULTS: Child and adolescent deaths decreased 51.7% from 13.77 million (95% uncertainty interval [UI], 13.60-13.93 million) in 1990 to 6.64 million (95% UI, 6.44-6.87 million) in 2017, but in 2017, but aggregate disability increased 4.7% to a total of 145 million (95% UI, 107-190 million) years lived with disability globally. Progress was uneven, and inequity increased, with low-SDI and low-middle-SDI locations experiencing 82.2% (95% UI, 81.6%-82.9%) of deaths, up from 70.9% (95% UI, 70.4%-71.4%) in 1990. The leading disaggregated causes of disability-adjusted life years in 2017 in the low-SDI quintile were neonatal disorders, lower respiratory infections, diarrhea, malaria, and congenital birth defects, whereas neonatal disorders, congenital birth defects, headache, dermatitis, and anxiety were highest-ranked in the high-SDI quintile.

CONCLUSIONS AND RELEVANCE: Mortality reductions over this 27-year period mean that children are more likely than ever to reach their 20th birthdays. The concomitant expansion of nonfatal health loss and epidemiological transition in children and adolescents, especially in low-SDI and middle-SDI countries, has the potential to increase already overburdened health systems, will affect the human capital potential of societies, and may influence the trajectory of socioeconomic development. Continued monitoring of child and adolescent health loss is crucial to sustain the progress of the past 27 years.

Language: en

LA - en SN - 2168-6211 UR - http://dx.doi.org/10.1001/jamapediatrics.2019.0337 ID - ref1 ER -