TY  - JOUR
PY  - 2019//
TI  - A case of drug-induced lung injury caused by kamikihito
JO  - Journal of UOEH
A1  - Tahara, Masahiro
A1  - Yamasaki, Kei
A1  - Ikegami, Hiroaki
A1  - Fukuda, Yoko
A1  - Uchimura, Keigo
A1  - Tachiwada, Takashi
A1  - Noguchi, Shingo
A1  - Kawanami, Toshinori
A1  - Kido, Takashi
A1  - Mukae, Hiroshi
A1  - Yatera, Kazuhiro
SP  - 51
EP  - 56
VL  - 41
IS  - 1
N2  - An eighty-nine-year-old Japanese male was admitted to our hospital due to dry cough and dyspnea. Respiratory symptoms appeared soon after an administration of an oriental medicine, Kamikihito for tinnitus. Upon admission, chest computed tomography showed patchy consolidations and ground-glass opacities in the right upper lobe of the lungs, and ground-glass opacities in the bilateral lower lobes. Sulbactam-ampicillin combination (SBT/ABPC, 3 g × 2/day) was started in addition to the change or cessation of several other drugs, including Kamikihito, resulting in respiratory symptoms and chest radiographic exacerbations. Bronchoalveolar lavage fluid obtained from the right S<sup>3</sup> showed an increase in the total cell number of lymphocytes. A drug lymphocyte stimulation test (DLST) for Kamikihito was also positive. Kamikihito-induced lung injury was most likely, and treatment with prednisolone (50 mg/day) was started. His respiratory symptoms and chest radiographic findings improved rapidly soon after initiating oral prednisolone. This is the first report of Kamikihito-induced lung injury.<p />  <p>Language: ja</p>
LA  - ja
SN  - 0387-821X
UR  - http://dx.doi.org/10.7888/juoeh.41.51
ID  - ref1
ER  -