TY - JOUR PY - 2019// TI - Functional Status Examination versus Glasgow Outcome Scale Extended as outcome measures in Traumatic Brain Injuries: how do they compare? JO - Journal of neurotrauma A1 - Dikmen, Sureyya A1 - Machamer, Joan A1 - Manley, Geoffrey T. A1 - Yuh, Esther Lim A1 - Nelson, Lindsay D. A1 - Temkin, Nancy R. SP - 2423 EP - 2429 VL - 36 IS - 16 N2 - Outcome measures are essential components of natural history studies of recovery and treatment effects following traumatic brain injury (TBI). The Glasgow Outcome Scale (GOS) and its revised version, the Glasgow Outcome Scale Extended (GOSE), are well accepted and widely used for both observational and intervention studies, but there are concerns about their psychometric properties and aptness as outcome measures for TBI. The present study compares the Functional Status Examination (FSE) with the GOSE to assess outcome following TBI in a sample of 533 participants with TBI from the Magnesium Sulfate study and the Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) study by evaluating the sensitivity of each measure to severity of brain injury and recovery of function over time. The results indicate that both measures are strongly correlated with TBI severity. At 3 months the correlation strengths between injury severity and each outcome measure do not differ (p=.92 for Glasgow Coma Scale (GCS), p=.14 for CT abnormalities) but at 6 months, the FSE is more strongly related to TBI severity indices than is the GOSE (p=.038 for GCS, p=.010 for CT abnormalities). In addition, the FSE generally shows significantly more improvement over time than the GOSE (p <.001). Detailed, structured administration rules and a wider score range of the FSE likely yields more sensitive and precise assessment of functional level than the GOSE. The FSE may be a valuable alternative to the GOSE for assessing functional outcome after TBI.

Language: en

LA - en SN - 0897-7151 UR - http://dx.doi.org/10.1089/neu.2018.6198 ID - ref1 ER -