TY  - JOUR
PY  - 2019//
TI  - Melanotan-induced priapism: a hard-earned tan
JO  - BMJ case reports
A1  - Dreyer, Barend Albert
A1  - Amer, Tarik
A1  - Fraser, Michael
SP  - e227644
EP  - e227644
VL  - 12
IS  - 2
N2  - Melanocortin analogues, such as melanotan, are illegally used for artificial tanning. They have also been suggested as possible therapeutic agents in the treatment of erectile dysfunction. This case study presents a patient attending the accident and emergency department, in a tertiary urology centre, with acute priapism after abdominal subcutaneous injection of melanotan. The priapism was diagnosed as 'low-flow' and managed with cavernosal aspiration, irrigation and subsequent intracavernosal injection of phenylephrine. The patient avoided requiring surgical shunting but had not yet recovered erectile function at 4-week follow-up. Acute priapism is an unreported side effect of melanocortin analogue use and this case report presents a patient managed without surgical intervention. Future therapeutic application of these agents will need to take this potential life altering complication into consideration.<br><br>© BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.<p />  <p>Language: en</p>
LA  - en
SN  - 1757-790X
UR  - http://dx.doi.org/10.1136/bcr-2018-227644
ID  - ref1
ER  -