TY  - JOUR
PY  - 2019//
TI  - Association between child maltreatment and central sensitivity syndromes: a systematic review protocol
JO  - BMJ open
A1  - Chandan, Joht Singh
A1  - Thomas, Tom
A1  - Raza, Karim
A1  - Bandyopadhyay, Siddhartha
A1  - Nirantharakumar, Krishnarajah
A1  - Taylor, Julie
SP  - e025436
EP  - e025436
VL  - 9
IS  - 2
N2  - INTRODUCTION: A growing body of evidence is identifying the link between a history of child maltreatment and a variety of adverse health outcomes ultimately leading to significant social and healthcare burden. Initial work has identified a potential association between child maltreatment and the development of a selection of somatic and visceral central sensitivity syndromes: fibromyalgia, chronic fatigue syndrome, temporomandibular joint disorder, chronic lower back pain, chronic neck pain, chronic pelvic pain, interstitial cystitis, vulvodynia, chronic prostatitis, tension-type headache, migraine, myofascial pain syndrome, irritable bowel syndrome and restless legs syndrome. <br><br>METHODS AND ANALYSIS: Primary electronic searches will be performed in the Embase, MEDLINE, PubMed, Scopus, PyscINFO, CINAHL and Cochrane Library databases and a number of Grey Literature sources including child protection and paediatric conference proceedings. Following independent screening of studies by two review authors, the Preferred Reporting Items for Systematic Reviews and Meta-Analyses template will be used to aid extraction. A meta-analysis will be conducted on the included case-control and cohort studies. The Newcastle-Ottawa grading system will be used to assess the quality of included studies. <br><br>RESULTS will be expressed as pooled ORs for binary data and mean differences for continuous data. ETHICS AND DISSEMINATION: Ethics approval will not be required. The final results of the review and meta-analysis will be submitted for peer-review publication and also disseminated at relevant conference presentations. PROSPERO REGISTRATION NUMBER: CRD42018089258.<br><br>© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.<p />  <p>Language: en</p>
LA  - en
SN  - 2044-6055
UR  - http://dx.doi.org/10.1136/bmjopen-2018-025436
ID  - ref1
ER  -